Compound Insights

The Compound Insights Inference Engine

Most compound databases give you rows. The engine gives you narrative claims with citations — binding mode, kinase class, PK parameters, regulatory history, off-target mechanisms — synthesised from primary literature by project fred, then joined with structured records from public sources (ChEMBL, UniProt, ClinicalTrials.gov, Reactome, Monarch, Open Targets). Every fred-derived claim carries a PubMed ID or DOI.

Choose a compound

Pilot · first compound

Imatinib

CHEMBL941 · Gleevec / Glivec

BCR-ABL / KIT / PDGFR tyrosine-kinase inhibitor across nine approved oncology indications. The first compound run end-to-end through the engine — a data-rich worked example with off-target landscape, AOP chains, and domain-reviewed provenance.

View dossier → Second compound

Orforglipron

CHEMBL4446782 · Foundayo / LY3502970

Oral non-peptide GLP-1 receptor agonist, FDA-approved April 2026. A deliberately data-sparse case: with thin structured records, the mechanistic inference layer carries proportionally more of the dossier — the engine's harder test.

View dossier →